U 73122
U- has also been used to study local calcium responses in human umbilical vein endothelial cells (HUVECs).
U 73122. U is a phospholipase C inhibitor. 2 It also exhibits inhibitory activity against HIV- 1 integrase with an IC 50 value of 7 µM. -68-7 U is a potent phospholipase C (PLC) inhibitor, which reduces agonist-induced Ca 2+ increases in platelets and PMN.
U- hydrate has been used for studying the role of phospholipase C (PLC) signaling in modulating epithelial Na + channel (ENaC) function in gerbil Reissner′s membranes (RMs). U- is an inhibitor of PLC- dependent processes, however, the mechanism of action remains unclear. Selleck's U has been cited by 22 publications.
The appropriate concentration will depend upon the cell type, cell density, medium concentration (the maleimide moiety of U- may react with thiol containing compounds) and the particular cell parameter that is being measured. 1, 2, 3 The IC 50 values for inhibition of platelet aggregation induced by collagen or thrombin are 0.6 and 5 µM, respectively. RUO - Research Use Only.
It inhibits agonist-induced platelet aggregation with IC50 values of 1-5 uM. For research use only. U- is a potent phospholipase C (PLC) inhibitor with IC50 value of ~6 μM.
U potently inhibits human 5-lipoxygenase (5-LO).
U Bml St391 Enzo Life Sciences
U An Aminosteroid Phospholipase C Inhibitor May Also Block Ca2 Influx Through Phospholipase C Independent Mechanism In Neutrophil Activation Semantic Scholar
Suppression Of M Current By Bk Is Attenuated By The Plc Inhibitor Download Scientific Diagram
U 73122 のギャラリー
The Phospholipase C Inhibitor U Blocks Both Agonist Activated Plc Download Scientific Diagram
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Effects Of The Phospholipase C Inhibitor U 1mm On Download Scientific Diagram
Mechanism Involved In Initiation And Propagation Of Receptor Induced Intercellular Calcium Signaling In Cultured Rat Astrocytes Journal Of Neuroscience
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Pdf The Putative Phospholipase C Inhibitor U And Its Negative Control U Elicit Unexpected Effects On The Rabbit Parietal Cell Semantic Scholar
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Effects Of The Phospholipase C Inhibitor U 10mm On Et 1 Induced Download Scientific Diagram
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Phosphoinositides Inositol Phosphates And Phospholipase C In Embryonic Stem Cells Springerlink
Inhibition Of Acetylcholine Activated K Currents By U Is Mediated By The Inhibition Of Pip 2 Channel Interaction Abstract Europe Pmc
Figure 1 From In Vivo Activity Of A Phospholipase C Inhibitor 1 6 17b 3 Methoxyestra 1 3 5 10 Trien 17 Yl Amino Hexyl 1h Pyrrole 2 5 Dione U In Acute And Chronic Inflammatory Reactions Semantic Scholar
Close Fig 5 Calcium Chelation Or Plc Inhibition Prevent Mc1r Mediated Enhancement Of Haoec Migration A After Insert Removal Haoec No C2 Monolayers Were Treated With A Msh 10 8 M With Or Without Pre Treatment With The Intracellular Ca2
The Phosphoinositide Specific Phospholipase C Inhibitor U 1 6 17b 3 Methoxyestra 1 3 5 10 Trien 17 Yl Amino Hexyl 1h Pyrrole 2 5 Dione Spontaneously Forms Conjugates With Common Components Of Cell Culture Medium Drug Metabolism Disposition
Plc G1 Signaling Plays A Subtype Specific Role In Postbinding Cell Entry Of Influenza A Virus Journal Of Virology
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U Standard Phospholipase C Plc Inhibitor Cas 68 7 Ab1998
Pharmacological Analysis Of Nod Factor Induced Calcium Spiking Inmedicago Truncatula Evidence For The Requirement Of Type Iia Calcium Pumps And Phosphoinositide Signaling Plant Physiology
U Supplier Cas 68 7 U Tocris Bioscience
The Phosphoinositide Specific Phospholipase C Inhibitor U 1 6 17b 3 Methoxyestra 1 3 5 10 Trien 17 Yl Amino Hexyl 1h Pyrrole 2 5 Dione Spontaneously Forms Conjugates With Common Components Of Cell Culture Medium Drug Metabolism Disposition
Regulation Of The Pacemaker Activities In Cultured Interstitial Cells Of Cajal By Citrus Unshiu Peel Extracts
Involvement Of Phospholipase C In Endothelin 1 Induced Stimulation Of Ca Channels And Basilar Artery Contraction In Rabbits In Journal Of Neurosurgery Volume 105 Issue 2 06
Effects Of Inhibition Of Phospholipase C With U 1 M On Ang Download Scientific Diagram
Regulation Of T Cell Activation And Tolerance By Phospholipase Cg 1 Dependent Integrin Avidity Modulation The Journal Of Immunology
U Inhibits Receptor Mediated Ca 2 Mobilization In Pmnls And Download Scientific Diagram
Inhibition Of Acetylcholine Activated K Currents By U Is Mediated By The Inhibition Of Pip 2 Channel Interaction Abstract Europe Pmc
Calcium Signaling Via Phospholipase C Is Essential For Proline Accumulation Upon Ionic But Not Nonionic Hyperosmotic Stresses In Arabidopsis Plant Physiology
U Reduces The Cell Growth In Cultured Mg 63 Ostesarcoma Cell Line Involving Phosphoinositide Specific Phospholipases C Springerplus Full Text
The Aminosteroid Phospholipase C Antagonist U 1 6 17 B 3 Methoxyestra 1 3 5 10 Trien 17 Yl Amino Hexyl 1h Pyrrole 2 5 Dione Potently Inhibits Human 5 Lipoxygenase In Vivo And In Vitro Molecular Pharmacology
The Aminosteroid Phospholipase C Antagonist U 1 6 17 B 3 Methoxyestra 1 3 5 10 Trien 17 Yl Amino Hexyl 1h Pyrrole 2 5 Dione Potently Inhibits Human 5 Lipoxygenase In Vivo And In Vitro Molecular Pharmacology
Effects Of Inhibition Of Plc With U 1 M Or Intracellular Download Scientific Diagram
Apexbio U
U 99 Hplc Selleck Phospholipase E G Pla Inhibitor
The Phosphoinositide Specific Phospholipase C Inhibitor U 1 6 17b 3 Methoxyestra 1 3 5 10 Trien 17 Yl Amino Hexyl 1h Pyrrole 2 5 Dione Spontaneously Forms Conjugates With Common Components Of Cell Culture Medium Drug Metabolism Disposition
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U An Aminosteroid Phospholipase C Inhibitor May Also Block Ca2 Influx Through Phospholipase C Independent Mechanism In Neutrophil Activation Semantic Scholar
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Effect Of The Phospholipase C Inhibitor U On Fbs Stimulated Insp Download Scientific Diagram
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U Cas 68 7 Calbiochem U Cas 68 7 Inhibits Agonist Induced Phospholipase C Activation Ic50 160 1 2 1 µm In Human Platelets And Neutrophils 68 7 Sigma Aldrich
Effects Of Ptx U 2 Apb Ki And Vpc321 On Lps And Download Scientific Diagram
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U Phospholipase C Inhibitor Medchemexpress
U An Aminosteroid Phospholipase C Inhibitor May Also Block Ca2 Influx Through Phospholipase C Independent Mechanism In Neutrophil Activation Semantic Scholar
The Effects Of Bradykinin On K Currents In Ng108 15 Cells Treated With U A Phospholipase C Inhibitor Or Neomycin Hildebrandt 1997 British Journal Of Pharmacology Wiley Online Library
U Cas 68 7 Calbiochem U Cas 68 7 Inhibits Agonist Induced Phospholipase C Activation Ic50 160 1 2 1 µm In Human Platelets And Neutrophils 68 7 Sigma Aldrich
Effects Of U And Its Analog U On The Hydrolysis Of 3 H Pip Download Scientific Diagram
Merck Millipore 默克密理博 6635 U Cas 68 7 Calbiochem
Multiple Roles For Plasmodium Berghei Phosphoinositide Specific Phospholipase C In Regulating Gametocyte Activation And Differentiation Raabe 11 Cellular Microbiology Wiley Online Library
U An Aminosteroid Phospholipase C Inhibitor May Also Block Ca2 Influx Through Phospholipase C Independent Mechanism In Neutrophil Activation Semantic Scholar
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U Phospholipase C Inhibitor Medchemexpress
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U Ligand Page Iuphar Bps Guide To Pharmacology
U Reduces The Cell Growth In Cultured Mg 63 Ostesarcoma Cell Line Involving Phosphoinositide Specific Phospholipases C Springerplus Full Text
Phospholipase C Linked Receptors Regulate The Atp Sensitive Potassium Channel By Means Of Phosphatidylinositol 4 5 Bisphosphate Metabolism Pnas
The Effects Of Bradykinin On K Currents In Ng108 15 Cells Treated With U A Phospholipase C Inhibitor Or Neomycin Hildebrandt 1997 British Journal Of Pharmacology Wiley Online Library
U Market Report Global Industry Size Segment By Key Companies Types Applications And
The Aminosteroid Phospholipase C Antagonist U 1 6 17 B 3 Methoxyestra 1 3 5 10 Trien 17 Yl Amino Hexyl 1h Pyrrole 2 5 Dione Potently Inhibits Human 5 Lipoxygenase In Vivo And In Vitro Molecular Pharmacology
U Phospholipase C Inhibitor Medchemexpress
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Jci Insight Activation Of The Calcium Sensing Receptor Attenuates Trpv6 Dependent Intestinal Calcium Absorption
The Phospholipase C Inhibitor U Inhibits Phorbol Ester Induced Platelet Activation Journal Of Pharmacology And Experimental Therapeutics
1 6 3 Methoxyestra 1 3 5 10 Trien 17 Yl Amino Hexyl 1h Pyrrole 2 5 Dione C29h40n2o3 Pubchem
Effects Of U And U On Human Platelet Calcium Signalling And Protein Tyrosine Phosphorylation Sciencedirect
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The Phospholipase C Inhibitor U Is A Potent Agonist Of The Polymodal Transient Receptor Potential Ankyrin Type 1 Trpa1 Receptor Channel Springerlink
Figure 2 From Phospholipase C In Living Cells Semantic Scholar
Anti Inflammatory Activities Of Phospholipase C Inhibitor U Inhibition Of Monocyte To Macrophage Transformation And Lps Induced Pro Inflammatory Cytokine Expression Sciencedirect
Figure 5 From In Vivo Activity Of A Phospholipase C Inhibitor 1 6 17b 3 Methoxyestra 1 3 5 10 Trien 17 Yl Amino Hexyl 1h Pyrrole 2 5 Dione U In Acute And Chronic Inflammatory Reactions Semantic Scholar
Pdf The Putative Phospholipase C Inhibitor U And Its Negative Control U Elicit Unexpected Effects On The Rabbit Parietal Cell Semantic Scholar
Effect Of U An Inhibitor Of Plc On The Centrally Administered Download Scientific Diagram
Calcium Mobilization Contributes To Pressure Mediated Afferent Arteriolar Vasoconstriction Hypertension
The Phosphoinositide Specific Phospholipase C Inhibitor U 1 6 17b 3 Methoxyestra 1 3 5 10 Trien 17 Yl Amino Hexyl 1h Pyrrole 2 5 Dione Spontaneously Forms Conjugates With Common Components Of Cell Culture Medium Drug Metabolism Disposition
68 7 U 1 6 17b 3 Methoxyestra 1 3 5 10 Trien 17 Yl Amino Hexyl 1h Pyr Role 2 5 Dione C H N O Trc
Inhibition Of Plc G1 Activity Converts Nerve Growth Factor From An Anti Mitogenic To A Mitogenic Signal In Cho Cells Oncogene
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Effects Of U And U On Human Platelet Calcium Signalling And Protein Tyrosine Phosphorylation Sciencedirect
Anti Inflammatory Activities Of Phospholipase C Inhibitor U Inhibition Of Monocyte To Macrophage Transformation And Lps Induced Pro Inflammatory Cytokine Expression Sciencedirect
Effects Of Genistein U And Staurosporine On r Mediated Ca 2 Download Scientific Diagram
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Effects Of U Phospholipase C Inhibitor On I Cch A After Download Scientific Diagram
High K Induced Contraction Requires Depolarization Induced Ca 2 Release From Internal Stores In Rat Gut Smooth Muscle Acta Pharmacologica Sinica
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